Microscopy Imaging and Analysis Publications

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2011

Aryl hydrocarbon receptor activation by TCDD reduces inflammation associated with Crohn's disease

Bioconjugated PLGA-4-arm-PEG branched polymeric nanoparticles as novel tumor targeting carriers

Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

Immunopathology of Postprimary Tuberculosis: Increased T-Regulatory Cells and DEC-205-Positive Foamy Macrophages in Cavitary Lesions

Quantum Dots Brighten Biological Imaging

SMAD-4-dependent barrier constrains prostate cancer growth and metastatic progression

The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis?

2010

Activation of NF- B by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4

Beta-Catenin/T-cell Factor Signaling Is Activated during Lung Injury and Promotes the Survival and Migration of Alveolar Epithelial Cells

Chromogens in multiple staining used for visual assessment and spectral imaging.

Cleaved caspase-3 in lung epithelium of children who died with acute respiratory distress syndrome

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer’s

Could recombinant insulin compounds contribute to adenocarcinoma progression by stimulating local angiogenesis?

Development of an orthotopic model of invasive pancreatic cancer in an immunocompetent murine host

Echinacea purpurea extracts modulate murine dendritic cell fate and function

Expression pattern of miR 146a, an inflammation associated microRNA, in experimental and human temporal lobe epilepsy

GPNMB expression in uveal melanoma: a potential for targeted therapy

Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes

Human Decidual Tissue Contains Differentiated CD8+ Effector-Memory T Cells with Unique Properties

Lateral reorganization of plasma membrane is involved in the yeast resistance to severe dehydration

Modulation of mismatch repair and genomic stability by miR-155

Multiplexed Analysis of Proteins in Tissue Using Multispectral Fluorescence Imaging

Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis

Persistent hyperinsulinemic hypoglycemia of infancy: constitutive activation of the mTOR pathway with associated exocrine-islet transdifferentiation and therapeutic implications

Photosensitization of CdSe/ZnS QDs and reliability of assays for reactive oxygen species production

Quantitative, Architectural Analysis of Immune Cell Subsets in Tumor-Draining Lymph Nodes from Breast Cancer Patients and Healthy Lymph Nodes

Quantitative, architectural analysis of immune cell subsets in tumor-draining lymph nodes from breast cancer patients and healthy lymph nodes

S100A8/A9 is not involved in host defense against murine urinary tract infection

S100A8/A9 is not involved in host defense against murine urinary tract infection

The quantitative detection of total HER2 load by quantum dots and the identification of a new subtype of breast cancer with different 5-year prognosis

The utility of in situ detection, including RT in situ PCR, of viral nucleic acid and the co-localization of the cytokine response to the study of viral pathogenesis

The utility of in situ detection, including RT in situ PCR, of viral nucleic acid and the co-localization of the cytokine response to the study of viral pathogenesis

Ultrasensitive in situ visualization of active glucocerebrosidase molecules

Use of quantum dots in the development of assays for cancer biomarkers

VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer

Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme

Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme

2009

3D cryo-imaging: a very high-resolution view of the whole mouse

A systems pathology model for predicting overall survival in patients with refractory, advanced non-small-cell lung cancer treated with gefitinib

Bystander effects induced by diffusing mediators after photodynamic stress

Chronic low-level lead exposure affects the monoaminergic system in the mouse superior olivary complex

Cys-diabody quantum dot conjugates (ImmunoQdots) for cancer marker detection

Haematopoietic stem cell migration to the ischemic damaged kidney is not altered by manipulating the SDF-1/CXCR4-axis

Histologic Graft Assessment After Clinical Islet Transplantation

Identification of CD44v6 plus/CD24 minus breast carcinoma cells in primary human tumors by quantum dot-conjugated antibodies

Imaging of laser-excited tissue autofluorescence bleaching rates

Mn-doped near-infrared quantum dots as multimodal targeted probes for pancreatic cancer imaging

Molecular regulation of hepatic dendritic cell function and its relation to liver transplant outcome

Moving beyond color: The case for multispectral imaging in brightfield pathology

Multispectral fluorescence imaging

New Variants of Epithelial-Myoepithelial Carcinoma: Oncocytic-Sebaceous and Apocrine

Review of imaging solutions for integrated quantitative immunohistochemistry in the Pathology daily practice

2008

A Dual-label Technique for the Immunohistochemical Demonstration of T-Lymphocyte Subsets in Formalin-fixed, Paraffin-Embedded Rat Lymphoid Tissue

A generally applicable sequential alkaline phosphatase immunohistochemical double staining

ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin

ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin.

Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers

Antitumor effect of the angiogenesis inhibitor bevacizumab is dependent on susceptibility of tumors to hypoxia-induced apoptosis

Automated localization and quantification of protein multiplexes via multispectral fluorescence imaging

Beyond morphology: whole slide imaging, computer-aided detection, and other techniques

Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity

Clinical quantitation of immune signature in follicular lymphoma by RT-PCR-based gene expression profiling

Comparison of hypoxia-inducible factor-1alpha expression before and after transcatheter arterial embolization in rabbit VX2 liver tumors

Diffusion-weighted PROPELLER MRI for quantitative assessment of liver tumor necrotic fraction and viable tumor volume in VX2 rabbits

Effect of ligand density on the spectral, physical, and biological characteristics of CdSe/ZnS quantum dots

Enhanced mobilization of bone marrow cells does not ameliorate renal fibrosis

Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis

Identification of Morphological Biosignatures in Martian Analogue Field Specimens Using In Situ Planetary Instrumentation

Lymphatic invasion revealed by multispectral imaging is common in primary melanomas and associates with prognosis

Multiple immunoenzyme staining: methods and visualizations for the observation with spectral imaging

Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of -catenin in prostate cancer

Quantitative multiplexed quantum dot immunohistochemistry

Quantum Dot Nanobarcodes: Epitaxial Assembly of Nanoparticle−Polymer Complexes in Homogeneous Solution

Quantum dots light up pathology

Simple quantification of multiplexed Quantum Dot staining in clinical tissue samples

The regulation and function of the forkhead transcription factor, Forkhead box O1, is dependent on the progesterone receptor in endometrial carcinoma

Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer

2007

A comparison of dispersing media for various engineered carbon nanoparticles

Anthrax Lethal Toxin Inhibits Growth of and Vascular Endothelial Growth Factor Release from Endothelial Cells Expressing the Human Herpes Virus 8 Viral G Protein–Coupled Receptor

Bioconjugated quantum dots for multiplexed and quantitative immunohistochemistry

Comparable frequencies of CD4+CD25+Foxp3+GITR+ regulatory T cells in normal skin and different inflammatory dermatoses

Effect of Transcatheter Arterial Embolization on Levels of Hypoxia-inducible Factor-1 [alpha] in Rabbit VX2 Liver Tumors

Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN

Immunohistochemical analysis of regulatory T cell markers FOXP3 and GITR on CD4+ CD25+ T cells in normal skin and inflammatory dermatoses

Immunoprofile of endocervical and endometrial stromal cells and its potential application in localization of tumor involvement

Improved prediction of prostate cancer recurrence through systems pathology

Liquid-crystal tunable filter spectral imaging for brain tumor demarcation

Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions

Quantum dots for cancer molecular imaging

Quantum dots for in vivo molecular and cellular imaging

Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress

Rab6 is increased in Alzheimer’s disease brain and correlates with endoplasmic reticulum stress

Semiautomated multiplexed quantum dot-based in situ hybridization and spectral deconvolution

Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen

Validation of novel optical imaging technologies: the pathologists' view

2006

Imaging of multiple mRNA targets using quantum dot based in situ hybridization and spectral deconvolution in clinical biopsies

Multiplexing immunohistochemical assays of clinical importance for epidermal growth factor receptor inhibitors

Photophysics of dopamine-modified quantum dots and effects on biological systems

Quantification of immunohistochemistry—issues concerning methods, utility and semiquantitative assessment II

2005

Detection of malignancy in cytology specimens using spectral-spatial analysis

MSI in small (and very small) animals

Multiple staining in molecular pathology

Nanomolecular histopathology for renal tumor classification

Quantum dots as phototoxic drugs and sensors of specific metabolic processes in living cells